Will's Words of Wisdom

Clinical Trail  Title: The Promise of Rectal Dexmedetomidine Niosomes for Pediatric Cancer Patients: Exploring Population Pharmacokinetics and Pharmacodynamics Cancer is a devastating disease that affects millions worldwide and poses unique challenges, particularly in the pediatric population. Managing postoperative pain in young cancer patients is crucial for their recovery as well as their overall well-being. The search for safe and effective analgesic interventions has led researchers to explore innovative approaches, such as the use of nanoparticles. In this blog post, we dive into a clinical trial titled "The Population Pharmacokinetics and Pharmacodynamics of Rectal Dexmedetomidine Niosomes Administered for Postoperative Analgesia in Pediatric Cancer Patients." This study investigates the potential of rectal dexmedetomidine niosomes as a novel analgesic therapy for children undergoing cancer treatment. Dexmedetomidine, a selective α2-adrenergic agonist, has gained atte...

  On Tuesday of this week our class had the privilege of hearing from Dr. Charli Fant talk to our class about herself and the work that she is doing at Zoetis! Dr. Fant is an alum of Transylvania University and went on to get her PhD and is now working in industry! It was a great opportunity for our class to hear from and talk with someone who had been sitting in the same seats as all of us not that long ago!  Zoetis  Zoetis is an animal health company that is developing as well as manufacturing veterinary medicines, vaccines, and diagnostic products for livestock as well as companion animals. They are a stop animal health company that has the mission to improve the health of animals and make a positive impact on the world during the process! On Zoetis website I saw that there is an importance on the development of genomic tools that can be used to improve animal health. They are working to try and better understand the genetic makeup of animals to help develop targeted s...

One of my favorite electron micrographs is of a bed bug that is taken using a scanning electron microscope (SEM). This image can be found on the Live Science website (https://www.livescience.com/19060-gallery-microscopic-images-viruses-bacteria-insects.html).  This SEM image show the body of a bed bug that is about 5 mm long. The insect seems to have a tough exoskeleton that gives a shield-like appearance, The antennae, legs, and sharp proboscis used for blood feeding are also very visible in this image.  I personally find it particularly interesting to see the level of detail in this image! The SEM uses electrons to scan the surface of the bug and creates a highly magnified 3D image with incredible resolution. The image shows the individual hairs on the legs and antennae, as well as the ridges and pores that are on the exoskeleton. SEM is a powerful tool for studying the morphology and structure of insects and other small organisms. Unlike traditional light microscopes, which...

In this post I will be discussing what all I was able to learn about and see on my classes second field trip back to the ASTeCC lab at The University of Kentucky! Is trip was specific to the Electron Microscopy Center (EMC) at UK! This machine that I am next to is an electron microscope that uses SEM. It uses a beam of electrons to detect and give an image of your sample. In this specific type of SEM, secondary electrons are used by atoms that are caused by its' electron beam that is detected by a secondary electron detector. With this type of machine it is very helpful if the sample is coated with a metal for better conductivity. The SEM operates at high pressures, which is better for biological samples. One draw back is that with a low vacuum, the resolution is not as good.  This is an image taken of a beetle with an automated microscope! This type of machine is able to detect wavelength, which allows us to have this really amazing colors that would not be able to be seen with a ...

Hello! It's very since to see you back here again with another post about what has been happening so far this week!  On Tuesday our class had the opportunity to go to the University of Kentucky's Advance Science and Technology Commercialization Center (ASTeCC Lab)! This lab and program allows for the University of Kentucky to do research and for different discoveries to be made and then possibly be put into the market. ASTeCC is a way for engineers and scientists with different back grounds to come together and possibly discover collaborative research of intellectual and commercial value.  During our visit at UK we were able to visit 4 different rooms and spend about 20 minutes in each of them, but I was not able to go into all of the different devices what we were able to see. Photonics  We were able to learn about photonics and using a passive wavelength to test different photonic chips. I was able to learn about the amazing things that go into photons! Electronic data ...

                                                                                         Hello! My name is Will Darnell and I am a rising senior at Transylvania University in Lexington, Ky! I am a Biology Major and Psychology Minor and I hope to one day become a Clinical Psychologist. My hope is to one day work with children with disabilities. I have two goldendoodles, Skye is on the right and Aeli is on the left!  I am currently enrolled in a course called Nanoscience that is taught by Drs. Johnson and Sly! I have created this blog as a way for me to spread my knowledge about the field of nanoscience and nanotechnology as I progress through this course! I honestly decided to enroll and take this course because I had basically no i...